Greater preference for eveningness is associated with negative symptoms in an ultra-high risk for psychosis sample

JJ Shetty; C Nicholas; B Nelson; PD McGorry; S Lavoie; C Markulev; MR Schäfer; A Thompson; HP Yuen; AR Yung; DH Nieman; L de Haan; GP Amminger; JA Hartmann

Journal article

Greater preference for eveningness is associated with negative symptoms in an ultra-high risk for psychosis sample

JJ Shetty, C Nicholas, B Nelson, PD McGorry, S Lavoie, C Markulev, MR Schäfer, A Thompson, HP Yuen, AR Yung, DH Nieman, L de Haan, GP Amminger, JA Hartmann

Early Intervention in Psychiatry | WILEY | Published : 2021

DOI: 10.1111/eip.13112

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Abstract

Aim: Investigating biological processes in at-risk individuals may help elucidate the aetiological mechanisms underlying psychosis development, refine prediction models and improve intervention strategies. This study examined the associations between sleep disturbances, chronotype, depressive and psychotic symptoms in individuals at ultra-high risk for psychosis. Methods: A sample of 81 ultra-high risk patients completed clinical interviews and self-report assessments of chronotype and sleep during the Neurapro clinical trial. Mixed regression was used to investigate the cross-sectional associations between symptoms and sleep disturbances/chronotype. Results: Sleep disturbances were signific..

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University of Melbourne Researchers

Christian Nicholas Author

Barnaby Nelson Author

Patrick McGorry Author

Suzie Lavoie Author

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Awarded by Novartis

Funding Acknowledgements

Melbourne School of Psychological Sciences, Grant/Award Number: McKenzie Postdoctoral Fellowship; National Health and Medical Research Council, Grant/Award Numbers: 1027532, 1060996, 1080963, 566529, 566593; Stanley Medical Research Institute, Grant/Award Number: 07TGF-1102; The Colonial Foundation